Douglas E. Brenneman
Company: Neuropathix, Inc.
Job title: Director of Pharmacology
GPR55, A Sentinel for Inflammation in Chemotherapy-Induced Peripheral Neuropathy 2:30 pm
Paclitaxel increases acute GPR55 expression in the cell bodies of DRG neurons KLS-13019, a novel cannabinoid, can act as a GPR55 antagonist to lysophosphatidylinosital-mediated increases in b-arrestin of DiscoverX cells KLS-13019 can reverse paclitaxel-induced increases in multiple cytokines, NLRP3 and GPR55 expression in high content assays of DRG neuronsRead more
day: Day Two